Author

Yong-Yuan Zhang

Virology, HBVtechORCID 0000-0001-9337-1553Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Bai-Hua ZhangiD· 1 shared Ben Tempel· 1 shared Fabien ZoulimiD· 1 shared Honggang Pan· 1 shared Jianming HuiD· 1 shared Laura Luckenbaugh· 1 shared Stephen K. HorriganiD· 1 shared Yuanping ZhouiD· 1 shared

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2025-2025 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperMicrobiology

Bai-Hua ZhangORCID

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1 paper

Recent·Most cited

MicrobiologyJournal of VirologyPeer-reviewedNov 6, 2025

Replication-driven HBV cccDNA loss in chimeric mice with humanized livers

Bai-Hua Zhang, Yuanping Zhou, Ben Tempel…·Yong-Yuan Zhang

This study shows that replication-driven cccDNA loss occurs in HBV-infected chimeric mice with humanized livers, and blocking cccDNA replenishment pathways significantly reduces cccDNA levels.

7 citations

mouseexperimental assay

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