Author

Michael D. Bobardt

Scripps Research InstituteORCID 0000-0001-9341-4373Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Philippe A. GallayiD· 2 shared Adolfo García‐SastreiD· 1 shared Asha Z. GoodmaniD· 1 shared Audrey Thomson· 1 shared Bo Hjorth BentzeniD· 1 shared Briana Lynn McGoverniD· 1 shared Daniel J. HadersiD· 1 shared Davey Smith· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPharmacology & Toxicology

Philippe A. GallayORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyPharmaceuticalsPeer-reviewedOct 18, 2026

MDL-001: an Oral, Direct-Acting Broad-Spectrum Antiviral for Influenza-Like Illness (ILI) and Chronic Hepatitis In Vivo

Virgil L. Woods, Tyler J. Umansky, Sean M. Russell…·Daniel J. Haders

This paper evaluates MDL-001, a broad-spectrum antiviral, showing potent in vitro and in vivo activity against influenza, RSV, SARS-CoV-2, and hepatitis B/C/D viruses, with improved efficacy compared to existing treatments.

DOI 10.3390/ph19101639

mouseexperimental assay

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Molecular BiologyPLoS PathogensPeer-reviewedAug 7, 2023

Post-infection treatment with the E protein inhibitor BIT225 reduces disease severity and increases survival of k18-hACE2 transgenic mice infected with a lethal dose of SARS-CoV-2

Gary D. Ewart, Michael D. Bobardt, Bo Hjorth Bentzen…·Philippe A. Gallay

This paper shows that BIT225, an E-protein inhibitor, reduces disease severity and increases survival in SARS-CoV-2 infected mice when administered before or after infection.

15 citations

mouseexperimental assay

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