Author

Paul Andrew Clarke

Institute of Cancer ResearchORCID 0000-0001-9342-1290Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Angeline E. Gavard· 1 shared Carrow I. WellsiD· 1 shared David Harold DrewryiD· 1 shared H. AitkenheadiD· 1 shared Hadley E. SheppardiD· 1 shared Hans J. OhiD· 1 shared Joseph A. NewmaniD· 1 shared Louisa TemmeiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Angeline E. Gavard

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintJun 6, 2024

Structures of the human transcription factor brachyury offer insights into DNA recognition, and identify small molecule binders for the development of degraders for cancer therapy

Joseph A. Newman, Angeline E. Gavard, Nergis Imprachim…·David Harold Drewry

This study determines the structure of human brachyury, identifies DNA binding insights and a G177D variant, and discovers small molecule binders for potential cancer therapy.

DOI 10.1101/2024.06.06.597736

humanprotein structure

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