NeuroscienceeLifePeer-reviewed
The novel role of Kallistatin in linking metabolic syndromes and cognitive memory deterioration by inducing amyloid-β plaques accumulation and tau protein hyperphosphorylation
Weiwei Qi, Yanlan Long, Ziming Li…·Guoquan Gao
This paper identifies Kallistatin's role in linking metabolic syndromes to cognitive decline by promoting amyloid-β plaques and tau hyperphosphorylation through Notch1 and GSK-3β pathways, and suggests fenofibrate as a potential treatment.
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