Anna D. Senft

ZFP661 blocks cohesin trapping by CTCF and increases protocadherin diversity for proper cortical dendritic arborization.

This study shows that MLL3/MLL4 methyltransferase activities are essential for early embryonic development and stem cell differentiation, but their role is lineage-selective and not dependent on enhancer activation.

This study investigates the roles of Nodal and Bmp signaling in primordial germ cell development using conditional deletions in mice, revealing distinct functions of Smad effectors in PGC specification, maintenance, and migration.