Hector L. Franco

This study identifies regulatory elements that switch from silencers to enhancers in breast cancer cells using single-cell ATAC-seq and RNA-seq data.

This study presents single-cell transcriptional and epigenetic profiles of male breast cancer to identify cancer-specific enhancers and their regulatory roles.

The paper optimizes CRISPR-based knockin strategies for editing multi-allelic proteins in cancer cells, demonstrating successful mutation of FOXA1 in MCF-7 cells.