Author

Hyunsoo Kim

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Biochemistry· 1 Genomics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aatish ThennavaniD· 1 shared Daewon Jeong· 1 shared Eui-Soon Park· 1 shared Han-Woong Lee· 1 shared Hector L. FrancoiD· 1 shared Hong-In Shin· 1 shared Jae-Ryong Kim· 1 shared Jaerang Rho· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Aatish ThennavanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

FragDockRL: A Reinforcement Learning Method for Fragment-Based Ligand Design via Building Block Assembly and Tethered Docking

Seung Hwan Hong, Hyunsoo Kim, Sejin Kim, Soosung Kang

FragDockRL uses reinforcement learning to design ligands by assembling building blocks and tethered docking, outperforming random search on three protein targets.

Journal of Chemical Information and Modeling · Oct 8, 2026Peer-reviewedBiochemistry

Single-Cell Transcriptional and Epigenetic Profiles of Male Breast Cancer Nominate Salient Cancer-Specific Enhancers

Hyunsoo Kim, Kamila Wiśniewska, Matthew J. Regner, Aatish Thennavan, Philip M. Spanheimer, Hector L. Franco

This study presents single-cell transcriptional and epigenetic profiles of male breast cancer to identify cancer-specific enhancers and their regulatory roles.

International Journal of Molecular Sciences · Aug 22, 2023Peer-reviewedGenomics

Gradual repression of selenoprotein W ensures physiological bone remodelling

Hyunsoo Kim, Kyunghee Lee, Jin Man Kim, Jae-Ryong Kim, Han-Woong Lee, Youn Wook Chung, Hong-In Shin, Eui-Soon Park, Jaerang Rho, Seoung Hoon Lee, Nacksung Kim, Soo Young Lee, Yongwon Choi, Daewon Jeong

This study identifies SELENOW as a regulator of osteoclast differentiation and bone remodelling, showing its repression by RANKL signaling prevents osteoporosis.

bioRxiv · Jan 26, 2018 · PreprintPhysiology