Author

Prashant Chandra Singh

Indian Association for the Cultivation of ScienceORCID 0000-0001-9357-9039Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Asim BisoiiD· 3 shared Akash Chatterjee· 1 shared Bipasa ChaudhuriiD· 1 shared Deepak Kumar SinhaiD· 1 shared Dipanjan RayiD· 1 shared Prosenjit SeniD· 1 shared Subhojit PauliD· 1 shared Sunipa SarkariD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 17 mutual co-author links

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3 shared papersBiochemistry

Asim BisoiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Hydroxychloroquine alters the cytoskeleton to impair cell migration

Dipanjan Ray, Asim Bisoi, Bipasa Chaudhuri, Prashant Chandra Singh, Deepak Kumar Sinha

This study shows hydroxychloroquine impairs cell migration by disrupting actin and vimentin cytoskeletal dynamics and altering cell mechanics.

bioRxiv · May 19, 2026 · PreprintCell Biology

G-Quadruplex Mediated c-myc Specific Downregulation: A Unique Pathway of the Anticancer Action of Immunomodulator Drugs

Sunipa Sarkar, Akash Chatterjee, Subhojit Paul, Asim Bisoi, Prosenjit Sen, Prashant Chandra Singh

This study shows that HCQ and CQ downregulate c-myc oncogene transcription via G4 stabilization, reducing tumor growth and enhancing chemotherapy in breast cancer models.

Journal of Biological Chemistry · Sep 23, 2025Peer-reviewedBiochemistry

Chemical Environment of the Confinement Governs Thermal Stability of the Folded Telomere G-Quadruplex

Trideep Majumdar, Asim Bisoi, Prashant Chandra Singh

This study investigates how the chemical nature of confinement affects the folding and thermal stability of telomere G-quadruplexes, finding that cationic water pools reduce thermal stability compared to anionic ones.

bioRxiv · May 8, 2025 · PreprintBiochemistry