Author

Prosenjit Sen

Indian Association for the Cultivation of ScienceORCID 0000-0002-1233-1822Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. BanerjeeiD· 1 shared Akash Chatterjee· 1 shared Arnab Ghosh· 1 shared Arpana Singh· 1 shared Asim BisoiiD· 1 shared Avinandan BhoumickiD· 1 shared Dhamodharan PrabhuiD· 1 shared K. SekariD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

A. BanerjeeORCID

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3 papers

Recent·Most cited

BiochemistryJournal of Biological ChemistryPeer-reviewedSep 23, 2025

G-Quadruplex Mediated c-myc Specific Downregulation: A Unique Pathway of the Anticancer Action of Immunomodulator Drugs

Sunipa Sarkar, Akash Chatterjee, Subhojit Paul…·Prashant Chandra Singh

This study shows that HCQ and CQ downregulate c-myc oncogene transcription via G4 stabilization, reducing tumor growth and enhancing chemotherapy in breast cancer models.

3 citations

mousebulk RNA-seq

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Cancer BiologyACS Biomaterials Science & EngineeringPeer-reviewedJan 3, 2025

Design and synthesis of triazine-based hydrogel for combined targeted doxorubicin delivery and PI3Kinhibition

Subhasis Mandal, Avinandan Bhoumick, Arpana Singh…·Prosenjit Sen

This study synthesizes triazine-based hydrogels that deliver doxorubicin and inhibit PI3K, showing improved biocompatibility and reduced side effects for melanoma treatment.

1 citation

experimental assaydrug response / drug discovery

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BioinformaticsbioRxivPreprintOct 13, 2022

Identification of potent anti-fibrinolytic compounds against plasminogen and tissue-type plasminogen activator using computational approaches

Suparna Banerjee, Yeshwanth Mahesh, Dhamodharan Prabhu…·Prosenjit Sen

The paper identifies potential anti-fibrinolytic compounds by screening the ZINC database using computational methods and validates their binding properties through simulations and analysis.

DOI 10.1101/2022.10.13.512028

statistical modeldrug response / drug discovery

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