Author

Marcelo Francia

University of California, Los AngelesORCID 0000-0001-9388-552XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Organism:Drosophila· 1 Approach:experimental assay· 1

Frequent Co-Authors

Merel H.M. BotiD· 2 shared Roel A. OphoffiD· 2 shared Toni A. BoltziD· 2 shared Alfredo GhezziiD· 1 shared Anouk den BraberiD· 1 shared Betty Marije TijmsiD· 1 shared Carlos J. Pacheco-Agosto· 1 shared Charlotte Elisabeth TeunisseniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Merel H.M. BotORCID

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3 papers

Recent·Most cited

Quantitative trait loci mapping of circulating metabolites in cerebrospinal fluid to uncover biological mechanisms involved in brain-related phenotypes

Lianne Maria Reus, Toni A. Boltz, Marcelo Francia, Merel H.M. Bot, Naren Ramesh, Maria Koromina, Yolande A.L. Pijnenburg, Anouk den Braber, Wiesje M. van der Flier, Pieter Jelle Visser, Sven J. van der Lee, Betty Marije Tijms, Charlotte Elisabeth Teunissen, Loes M. Olde Loohuis, Roel A. Ophoff

This study maps quantitative trait loci for CSF metabolites and identifies associations with brain traits, revealing potential neurobiological pathways.

Molecular Psychiatry · Feb 28, 2025Peer-reviewedGenomics

Fibroblasts as an in vitro model of circadian genetic and genomic studies

Marcelo Francia, Merel H.M. Bot, Toni A. Boltz, Juan De La Hoz, Marco P. Boks, René S. Kahn, Roel A. Ophoff

This study examines circadian genetic architecture in fibroblasts to assess its contribution to bipolar disorder risk, finding limited gene expression patterns and no significant genetic associations with BD.

bioRxiv · May 19, 2023 · PreprintGenomics

pumilio regulates sleep homeostasis in response to chronic sleep deprivation in Drosophila melanogaster

Luis A. De Jesús-Olmo, Norma Rodríguez, Marcelo Francia, Jonathan Alemán-Rios, Carlos J. Pacheco-Agosto, Joselyn Ortega-Torres, Richard Nieves, Nicolás Fuenzalida‐Uribe, Alfredo Ghezzi, José L. Agosto

This study shows that Pumilio is essential for sleep rebound, particularly after chronic sleep deprivation in Drosophila, by modulating neuronal excitability.

Frontiers in Neuroscience · Apr 17, 2020Peer-reviewedNeuroscience