Anouk den Braber

This study identifies 118 new genetic loci associated with Alzheimer's disease across diverse ancestries and discovers 48 novel risk loci, including those enriched in neuronal cell types.

This study maps quantitative trait loci for CSF metabolites and identifies associations with brain traits, revealing potential neurobiological pathways.

The paper performs a GWAS on PSP in the Iberian population, replicates known risk variants, and identifies a novel locus in NFASC/CNTN2 associated with oligodendrocyte and myelination processes.

The paper analyzes cortical thickness trajectories in 17,075 individuals to show peak thickness in childhood, steep decline in early adulthood, and slower decline later, with notable exceptions and significant inter-individual variability.

The paper analyzes sex differences in brain structure variability across the lifespan using a large dataset, finding greater male variability in subcortical volumes, cortical surface area, and thickness in most regions.

This study analyzes subcortical volume changes across the lifespan using MRI data from 18,605 individuals, finding age-related declines in some structures and increases in others.

The paper identifies genetic loci associated with human cortical structure and finds genetic correlations with neuropsychiatric disorders.

This paper investigates genetic correlations between compulsive symptoms and OCD using GWAS and finds novel genes and increased enrichment for brain-related genes when combining symptom data with case-control studies.

The paper reports epigenome-wide meta-analyses of blood DNA methylation with subcortical brain volumes, identifying significant associations with hippocampal volume and potential biological mechanisms.

This study estimates heritability and genetic contributions to metabolite levels using genome-wide data and twin-family cohorts, revealing class-specific genetic influences.

The paper identifies 25 genetic loci associated with subcortical brain structure volumes in over 40,000 individuals, revealing novel biology and potential drug targets.

The paper evaluates 15 candidate SNPs associated with psychiatric disorders using 6,165 diffusion MRI scans, finding no significant associations after correction for multiple testing.