Cell BiologyThe Journal of Cell BiologyPeer-reviewed
Cargo adaptors use a handhold mechanism to engage with myosin V for organelle transport
Hye Jee Hahn, Natalya Pashkova, Michael A. Cianfrocco, Lois S. Weisman
The paper shows that cargo adaptors bind myosin V through multiple sites, using a handhold mechanism to enhance motor-cargo interactions and regulation.