Kyogo Kawaguchi

The paper shows that the mammalian heart functions as a chiral nematic field, with topological defects influencing contractile mechanics and efficiency.

The paper identifies coding DNA sequence density as a universal predictor of chromatin compartmentalization across species, revealing its conservation over evolutionary time.

This study reconstitutes gene-scale chromatin arrays with controlled histone modifications to show acetylation increases structural fluctuations and reduces nucleosome contact frequency.

APEX-Ribo-Seq maps local translation across organelles and identifies compartment-specific transcripts, revealing sequence features and dynamics of subcellular translation.

The paper induces +1 topological defects in neural progenitor cell monolayers and shows cells are attracted to their cores, challenging existing theories about active nematics.

The paper analyzes vertebral formulae across tetrapods to identify homeotic and non-homeotic patterns, revealing unexpected balances and correlations with Hox gene clusters.

LapTrack improves particle tracking by solving a linear assignment problem with customizable metrics and parallel parameter tuning, enhancing tracking accuracy on real and artificial datasets.