Michael L. Reese

A RabGAP-fold protein, TBC9, supplies the missing RanGAP activity in Toxoplasma; its acidic C-terminal motif promotes Ran binding and marks TBC9 orthologs across non-ciliate alveolates.

This study shows that RNS inhibit ROP5-mediated immune evasion in Toxoplasma gondii by modifying ROP5 through S-nitrosylation, reducing its association with the parasitophorous vacuole membrane.

This study identifies and characterizes novel nuclear pore complex components in Toxoplasma gondii, revealing divergence in mRNA export machinery compared to other eukaryotes.

This paper uses third-generation sequencing to revise the molecular karyotype of Toxoplasma gondii, identifying chromosome fusions and copy number variants in sexual recombinants.

The paper identifies WNG1, a divergent kinase in Toxoplasma, that regulates PV membrane ultrastructure through phosphorylation of PV-resident proteins.