Author

F. David Horgen

Hawaii Pacific UniversityORCID 0000-0001-9409-3030Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Alexander DietrichiD· 1 shared Anna MadlmayriD· 1 shared Birgit HoegeriD· 1 shared Christine Schedlberger· 1 shared Dorothea Lewitz· 1 shared Julia Eder· 1 shared Katharina Hörner· 1 shared Kilian HoeltingiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alexander DietrichORCID

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1 paper

Recent·Most cited

TRPM7 activity drives human CD4 T-cell activation and differentiation in a magnesium dependent manner

Anna Madlmayr, Kilian Hoelting, Birgit Hoeger, Dorothea Lewitz, Marius Weng, Severin Hacker, Julia Eder, Katharina Hörner, Christine Schedlberger, Tanja Haider, Max Lechner, Michelle Duggan, Rylee Ross, F. David Horgen, Markus Sperandio, , Susanna Zierler

This study shows TRPM7 is essential for human CD4 T-cell activation and differentiation through Mg2+ dependent Ca2+ signaling and NFAT translocation.

Life Science Alliance · Nov 17, 2025Peer-reviewedImmunology