Mitochondrial morphology and function in mitochondrial disease
Julie Faitg, Tracey Davey, Ross Laws, Conor Lawless, Helen A. L. Tuppen, Eric Fitton, Douglass M. Turnbull, Amy E. Vincent
This study uses COX-SBFSEM to examine mitochondrial morphology and function in human muscle biopsies with mtDNA deletions, revealing distinct mitochondrial populations and spatial patterns of oxidative phosphorylation.
bioRxiv · Dec 20, 2023 · PreprintMolecular Biology