Min Xiao

This study identifies TFAP2A as a driver of BRAF/MEK inhibitor resistance and immunosuppression, showing its disruption enhances antitumor immunity and overcomes drug resistance.

This study uses single-cell lineage tracing to map clonal and transcriptional dynamics in melanoma metastasis, identifying distinct transcriptional programs and spatial organization patterns.

This study identifies drug-tolerant persister states in melanoma using MeRLin, showing their role in resistance and tumor recurrence.

The paper identifies the MYC-ATF4-ASS1 axis in melanoma that controls arginine synthesis and modulates immune responses, showing therapeutic potential with arginine depletors and BRAF/MEK inhibitors.

The paper presents a pan-cancer PDX histology image repository with genomic and pathological annotations for deep learning analysis of tumor regions and xenograft-transplant lymphoproliferative disorder prediction.