Author

Maggie Dunne

The Wistar Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Research Focus:clustering· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Assay:spatial transcriptomics· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

Meenhard HerlyniD· 5 shared Haiyin LiiD· 4 shared Min XiaoiD· 4 shared Monzy Thomas· 4 shared Yeqing CheniD· 4 shared Arjun RajiD· 3 shared Haiwei MouiD· 3 shared Jessica KasteriD· 3 shared

Activity by Year

2025-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersCancer Biology

Meenhard HerlynORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

TFAP2A links drug resistance to antitumor immunity

Haiwei Mou, Veronika Yakovishina, Kristen M. DeRosa, Yeqing Chen, Min Xiao, Maggie Dunne, Nancy Shi, Monzy Thomas, Jordan L. Smith, Qin Liu, Meenhard Herlyn

This study identifies TFAP2A as a driver of BRAF/MEK inhibitor resistance and immunosuppression, showing its disruption enhances antitumor immunity and overcomes drug resistance.

bioRxiv · Jul 10, 2026 · PreprintCancer Biology

Single-cell lineage tracing maps clonal and transcriptional dynamics in melanoma metastasis

Haiyin Li, Yeqing Chen, Jessica Kaster, Maggie Dunne, Cong Qi, Ling Li, Min Xiao, Monzy Thomas, Nazifa Promi, Dylan F. Fingerman, Gregory Schuyler Brown, Qiuxian Zheng, Jessie Villanueva, Bin Tian, Xiaowei Xu, , Meenhard Herlyn

This study uses single-cell lineage tracing to map clonal and transcriptional dynamics in melanoma metastasis, identifying distinct transcriptional programs and spatial organization patterns.

bioRxiv · Apr 13, 2026 · PreprintCancer Biology

Clonal dynamics shaped by diverse drug-tolerant persister states in melanoma resistance

Haiyin Li, Yeqing Chen, Jessica Kaster, Maggie Dunne, Min Xiao, Ling Li, Monzy Thomas, Nazifa Promi, Dylan F. Fingerman, Gregory Schuyler Brown, Qiuxian Zheng, Xingyue Zhu, McKenna Reale, Andrew Patterson, Le Gao, , Meenhard Herlyn

This study identifies drug-tolerant persister states in melanoma using MeRLin, showing their role in resistance and tumor recurrence.

Molecular Cancer · Mar 3, 2026Peer-reviewedCancer Biology

MYC-ATF4-ASS1 axis governs intracellular arginine synthesis and dictates the immune microenvironment in melanoma

Haiwei Mou, Veronika Yakovishina, Yeqing Chen, Min Xiao, Maggie Dunne, Nancy Shi, Monzy Thomas, Kristen M. DeRosa, Haiyin Li, Qin Liu, Meenhard Herlyn

The paper identifies the MYC-ATF4-ASS1 axis in melanoma that controls arginine synthesis and modulates immune responses, showing therapeutic potential with arginine depletors and BRAF/MEK inhibitors.

bioRxiv · Mar 2, 2026 · PreprintCancer Biology

SpaceBar enables clone tracing in spatial transcriptomic data

Grant Kinsler, Caitlin Fagan, Haiyin Li, Jessica Kaster, Maggie Dunne, Robert Vander Velde, Ryan H. Boe, Sydney M. Shaffer, Meenhard Herlyn, Arjun Raj, Yael Heyman

SpaceBar enables clone tracing and spatial transcriptomics profiling by using synthetic barcodes to label cells and analyze gene expression in situ.

bioRxiv · Feb 10, 2025 · PreprintGenomics