Glen Pridham

The paper introduces a saturating removal model to explain end-of-life dynamics across species, showing it accurately captures morbidity patterns and predicts key phenomena in flies, mice, and humans.

The paper analyzes lab test dynamics during pregnancy and nonpregnancy to show age-related changes resembling both rejuvenation and aging in different physiological systems.

This paper estimates that the heritability of human lifespan is about 50% when accounting for extrinsic factors and cutoff age effects, challenging the consensus that genetics has a minor role in lifespan.