Author

Guangxu Jin

Atrium Health Wake Forest BaptistORCID 0000-0001-9451-4886Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Gang Xue· 1 shared Lance David MilleriD· 1 shared Ling‐Yun WuiD· 1 shared Rui JingiD· 1 shared Rui‐Sheng WangiD· 1 shared Tao MaiD· 1 shared Tiantian MaoiD· 1 shared Tony Jin· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Gang Xue

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2 papers

Recent·Most cited

CART-GPT: A T Cell-Informed AI Linguistic Framework for Interpreting Neurotoxicity and Therapeutic Outcomes in CAR-T Therapy

Tiantian Mao, Xiaojian Shao, Wei Guo, Zhiwu Jiang, Rui Jing, Xin Li, Yiran Zhu, Tony Jin, Tao Ma, Yong Lu, Guangxu Jin

CART-GPT predicts CAR-T therapy efficacy and neurotoxicity risk using a transformer model trained on 1.12 million single-cell RNA-seq profiles with clinical outcomes.

bioRxiv · Aug 8, 2025 · PreprintBioinformatics

Single-Cell Modeling of CD8+ T Cell Exhaustion Predicts Response to Cancer Immunotherapy

Guangxu Jin, Gang Xue, Rui‐Sheng Wang, Ling‐Yun Wu, Lance David Miller, Yong Lu, Wei Zhang

This paper introduces a single-cell computational method to predict cancer immunotherapy response by analyzing CD8+ T cell exhaustion profiles.

bioRxiv · Nov 2, 2018 · PreprintBioinformatics