Author

Yong Lu

Houston MethodistORCID 0009-0001-4250-7278Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yong Lu2 papers · University of Maryland, College Park

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Wei GuoiD· 2 shared Edward J. JacobsiD· 1 shared Guangxu JiniD· 1 shared Julio P. ArroyoiD· 1 shared Rafael V. DavalosiD· 1 shared Rui JingiD· 1 shared Sam Salamizadeh Parizi· 1 shared Tao MaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Wei GuoORCID

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2 papers

Recent·Most cited

Cancer BiologyResearchPeer-reviewedJan 1, 2026

Novel combination of irreversible electroporation and allogenic chimeric antigen receptor (CAR) T-cell therapy synergizes therapeutic outcomes in a preclinical human pancreatic cancer mouse model

Edward J. Jacobs, Julio P. Arroyo, Sam Salamizadeh Parizi…·Rafael V. Davalos

This study combines irreversible electroporation with CAR T-cell therapy to improve outcomes in a pancreatic cancer mouse model by targeting residual tumor cells post-ablation.

4 citationstop 1%

mouseexperimental assay

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BioinformaticsbioRxivPreprintAug 8, 2025

CART-GPT: A T Cell-Informed AI Linguistic Framework for Interpreting Neurotoxicity and Therapeutic Outcomes in CAR-T Therapy

Tiantian Mao, Xiaojian Shao, Wei Guo…·Guangxu Jin

CART-GPT predicts CAR-T therapy efficacy and neurotoxicity risk using a transformer model trained on 1.12 million single-cell RNA-seq profiles with clinical outcomes.

5 citations

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