Chiara Scaramuzzino

This study shows that HTT phosphorylation recruits KIF1A to enhance axonal transport of synaptic vesicle precursors, increasing glutamate release and impairing motor learning in mice.

This study shows that increasing HTT phosphorylation at Ser421 improves BDNF transport, striatal BDNF availability, and the phenotype of Mecp2 knockout mice.

This study shows that ATAT1-enriched vesicles are transported along axons to acetylate -tubulin, essential for proper vesicular transport.

This study shows polyglutamine-expanded androgen receptor disrupts muscle function by altering calcium dynamics and excitation-contraction coupling gene expression, which can be reversed by treatment.