Author

Lanlan Zhou

Brown UniversityORCID 0000-0001-9471-9099Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Wafik S. El‐DeiryiD· 2 shared Attila A. SeyhaniD· 1 shared Benedito A. CarneiroiD· 1 shared Kelsey E. HuntingtoniD· 1 shared Laura Jinxuan WuiD· 1 shared Leiqing ZhangiD· 1 shared Maximilian P. Pinho-SchwermanniD· 1 shared Ryan MalpassiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Wafik S. El‐DeiryORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 21, 2024

Tumor suppressor p73 transcriptionally regulates c-FLIP to impede its priming of extrinsic apoptosis while a switcher compound degrades c-FLIP protein

Shengliang Zhang, Lanlan Zhou, Wafik S. El‐Deiry

This study shows p73 upregulates c-FLIP to suppress extrinsic apoptosis, and a compound degrades c-FLIP to enhance p73's antitumor effects in p53-mutant cancers.

DOI 10.1101/2024.04.21.590479

humanexperimental assay

Cancer BiologyAmerican Journal of Cancer ResearchPeer-reviewedJan 1, 2024

Synergistic combination therapy with ONC201 or ONC206, Enzalutamide and Darolutamide in preclinical studies of castration-resistant prostate cancer

Laura Jinxuan Wu, Maximilian P. Pinho-Schwermann, Lanlan Zhou…·Wafik S. El‐Deiry

This study shows that combining ONC201 with enzalutamide or darolutamide synergistically reduces mCRPC cell viability and PSA levels, with in vivo anti-tumor effects.

7 citations

humanexperimental assay