Protein folding stress transcriptionally reprograms muscle metabolism
Jacob Paiano, Mujeeb Qadiri, Sonam Sharma, Yanhui Hu, Norbert Perrimon
This study shows that activating the UPR in muscle cells reprograms metabolism from carbohydrate to lipid metabolism through transcriptional changes.
bioRxiv · Jun 20, 2025 · PreprintCell Biology