Mujeeb Qadiri

A tiered catalogue of 5,280 Drosophila genes encoding putative secreted proteins (1,802 high-confidence) with a web portal; these genes are less conserved, more tissue-restricted and disproportionately down-regulated with age.

This study uses in-situ glial cell-surface proteomics in Drosophila to identify DIP-β as a pro-longevity factor regulated by glial cells.

This study presents a single-nucleus transcriptomic atlas of Drosophila treated with rapamycin, identifying a sex-biased convergent aging trajectory and its modulation by rapamycin.

This study maps central carbon metabolism in Hippo-Yki-driven Drosophila gut tumors, revealing conserved metabolic principles shared with mammalian cancer metabolism.

This study shows that renal CoA production from VB5 supports gut stem cell proliferation and tumor growth in Drosophila, with implications for human cancer.

This study uses a Drosophila model to show that CFTR loss reduces cholinergic signaling, which contributes to gut pathologies, and that restoring cholinergic signaling can rescue these phenotypes.

The paper identifies Zrf1 as an epigenetic factor regulating intestinal stem cell proliferation and genome stability in Drosophila midgut regeneration.

The paper introduces IntAC, a CRISPR screening method for Drosophila cells that improves accuracy by suppressing early Cas9 activity, leading to a more comprehensive list of fitness genes.

This study shows that activating the UPR in muscle cells reprograms metabolism from carbohydrate to lipid metabolism through transcriptional changes.

TF2TG integrates TF-DNA binding, protein-protein interactions, and transcriptomic data to identify and rank potential target genes for Drosophila transcription factors.