Lumei Huang

CO2-dependent opening of Connexin 43 hemichannels

The paper demonstrates that Cx43 hemichannels open in response to CO2, resolving a discrepancy between in vivo and in vitro studies.

CO2-sensitive Cx26 hemichannels in dorsal raphe-ventral tegmental area pathway mediate hypercapnic arousal

This study identifies Cx26 hemichannels as a CO2 sensor in serotonergic neurons that mediates hypercapnic arousal by enabling serotonin release.