Cell BiologybioRxivPreprint
Cell clusters are programmed towards a reductive metabolic 1 state by adherence junctions
Uttkarsh Ayyangar, Janhavi Sathe, Md. Faiz Ahmad, Sunil Laxman
The paper shows that cadherin junctions drive metabolic reprogramming in cell clusters, enhancing the pentose phosphate pathway and reducing ROS, with implications for multicellular organization.
DOI 10.1101/2025.10.02.680172