Epigenetic control of microglial mitochondrial immunity by KAT7 drives Alzheimer's disease pathogenesis
Yongqing Liu, Yingzhi Ye, Minghua Fan…·Zhaozhu Qiu
This study identifies KAT7 as an epigenetic regulator that drives microglial mitochondrial immunity and Alzheimer's disease pathogenesis by enhancing mtDNA-driven inflammation and amyloid-β burden.