Danica T. Schmidtke

The paper shows that the K5 capsular polysaccharide of E. coli Nissle 1917 sensitizes it to thioridazine and related antipsychotics, revealing CPS as a vulnerability under non-antibiotic drug pressure.

This study characterizes the crAssphage lifestyle as a phage-plasmid, demonstrating its persistence in the gut microbiome without causing host lysis or chromosomal integration.

The paper uses long-read metagenomics to study prophage integration dynamics in gut microbiota, finding dynamic phage-host interactions and a new class of phages.