Aravind Natarajan

The paper shows that the K5 capsular polysaccharide of E. coli Nissle 1917 sensitizes it to thioridazine and related antipsychotics, revealing CPS as a vulnerability under non-antibiotic drug pressure.

This study identifies sRNA 84 as a conserved regulator in Enterococcaceae that enhances mucin adhesion and gut colonization by upregulating cell surface proteins.

The paper identifies age-related microbiome metabolites that alter RNA splicing and chromatin accessibility in the mouse brain using metabolomics, transcriptomic, and multi-omic approaches.

The paper introduces a cell-free platform for assembling protein glycosylation pathways and demonstrates its use in creating vaccine proteins and antibody constant regions with specific glycan motifs.

This paper presents a cell-free platform for synthesizing active oligosaccharyltransferases (OSTs) and demonstrates its ability to produce and test multiple OSTs for glycosylation reactions.