Chi Zhang

This paper introduces a new expansion microscopy technique that fixes proteins directly to a hydrogel network to preserve nanoscale organization while enabling physical magnification.

This study adapts Edman degradation and amino acid recognition to expansion microscopy gels to demonstrate in situ protein sequencing principles using synthetic constructs.

The paper introduces umExM, a method for dense membrane labeling and expansion microscopy to achieve nanoscale visualization of membranes in tissues, demonstrating resolution down to ~35 nm.

The paper introduces a method to record cellular physiological histories using self-assembling protein chains that can be optically read, demonstrating its use in neurons and mouse brain.