Nuclear Receptor Transcription factors promote axon regeneration in the Adult Corticospinal Tract
Yogesh Sahu, Manojkumar Kumaran, Soupayan Banerjee, PS Athul Narayan, Katha Sanyal, Meghana Konda, Shringika Soni, Dhruva Kumar, Anisha S Menon, Prakash Chermakani, Aarthi Sukumar, Faheem Farooq, Sneha Manjunath, Deepta Susan Beji, Arupam Biswas, Ishwariya Venkatesh
This study identifies NR2F1 and NR2F6 as nuclear receptor transcription factors that promote axon regeneration in the corticospinal tract through chromatin remodeling, enhancer redeployment, and translational reprogramming.
bioRxiv · Jun 19, 2025 · PreprintNeuroscience