Deepta Susan Beji

This study shows that three-dimensional genome organization in adult neurons encodes regenerative potential, with injury partially reversing this structure to re-engage developmental gene programs.

This study identifies NR2F1 and NR2F6 as nuclear receptor transcription factors that promote axon regeneration in the corticospinal tract through chromatin remodeling, enhancer redeployment, and translational reprogramming.

This study maps chromatin accessibility changes in mouse forebrain development and shows that PATZ1 can reverse epigenetic restrictions in adult neurons to enhance axon regeneration after injury.