Author
University of North Carolina at Chapel HillORCID 0000-0001-9563-0125Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
6 papers
Recent·Most cited
Alejandro Gomez, Jessica C. McAfee, Hyunggyu Min…·Hyejung Won
This study identifies 38 expression-modulating variants associated with neurodevelopmental disorders and links them to neurodevelopmental transcriptional programs using MPRA and CROP-seq.
Nana Matoba, Jessica C. McAfee, Oleh Krupa…·Jason L. Stein
The paper assesses regulatory activity of cortical structure-associated variants using MPRA in human neural progenitor cells, identifying 918 variants with regulatory potential and showing condition-dependent effects.
R. Kijoon Kim, Catherine A. Smith, Natalie L. Truby…·Peter J. Hamilton
This study shows that altering TRIM28 function in the mouse prefrontal cortex leads to transposable element derepression and social behavior deficits, which can be reversed by interferon cytokines.
Marielle L. Bond, Ivana Yoseli Quiroga, Susan D’Costa…·Hyejung Won
The paper identifies 47 expression-modulating variants in AD-associated loci by analyzing their impact in immune cells under different inflammatory conditions.
Jessica C. McAfee, Sool Lee, Jiseok Lee…·Hyejung Won
The paper uses MPRA to identify functional regulatory variants associated with schizophrenia and shows they differ from eQTLs in genomic location and regulatory impact.
Melissa Plooster, Guendalina Rossi, Martilias S. Farrell…·Patrick Brennwald
This study identifies tSNARE1 as a schizophrenia risk gene that regulates endolysosomal trafficking in cortical neurons through its isoforms' effects on endosomal cargo movement.