Alessandro Piccin

This study shows that noradrenergic signaling in the orbitofrontal cortex adjusts learning rates based on environmental volatility, improving adaptive decision-making in rats.

This study shows that blocking the CRF1 receptor in male mice prevents morphine-induced sociability deficits and oxytocinergic neuron firing, with sex-specific effects.

This study shows that mPFC noradrenergic transmission is critical for updating stimulus-outcome associations after contingency degradation, while vlOFC is not involved.

This study shows that noradrenergic projections to the rodent orbitofrontal cortex are necessary for updating action-outcome relationships during reversal learning.