James G. Booth

This paper introduces NetFlow3D, a framework that integrates protein structure and interaction networks to identify significant mutation clusters and modules in cancer, revealing biological processes not found by traditional methods.

MAGMa is a tool for differential expression analysis in mass-spectrometry proteomic data, showing improved sensitivity and specificity in detecting true signals.

The paper identifies fundamental enhancer units defined by transcription start sites and shows adjacent units operate non-cooperatively.

The paper shows that human AMY1 gene copy number affects oral and gut microbiome composition and function, with low-AMY1 associated with enhanced complex carbohydrate breakdown and high-AMY1 linked to resistant starch fermentation and higher adiposity.