Shagun Gupta

Phosphatidylserine and RhoB connect phosphatidylinositol 4-phosphate and phosphatidic acid metabolism at the plasma membrane

The paper identifies a metabolic connection between PI4P and PA at the plasma membrane, showing how PI4P depletion increases PA levels through PS synthesis and RhoB activation.

A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology

This paper introduces NetFlow3D, a framework that integrates protein structure and interaction networks to identify significant mutation clusters and modules in cancer, revealing biological processes not found by traditional methods.

MAGMa: Your Comprehensive Tool for Differential Expression Analysis in Mass-Spectrometry Proteomic Data.

MAGMa is a tool for differential expression analysis in mass-spectrometry proteomic data, showing improved sensitivity and specificity in detecting true signals.

A 3D Structural Interactome to Explore the Impact of Evolutionary Divergence, Population Variation, and Small-molecule Drugs on SARS-CoV-2-Human Protein-Protein Interactions

The paper constructs a 3D structural interactome of SARS-CoV-2-human protein interactions, analyzing evolutionary divergence, population variation, and drug impacts.