Author

Patrick C. Fiaux

Salk Institute for Biological StudiesORCID 0000-0001-9614-7370Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:fine-mapping· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Aaron R. CheniD· 2 shared Graham McVickeriD· 2 shared Hsiuyi V. CheniD· 2 shared Aaron J. Ho· 1 shared Allison L. O’KelliD· 1 shared Andi FloryiD· 1 shared Angela L. McCleary‐WheeleriD· 1 shared Ariana Fonseca· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Aaron R. ChenORCID

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3 papers

Recent·Most cited

GenomicsAmerican Journal of Veterinary ResearchPeer-reviewedDec 27, 2023

Next-generation sequencing-based liquid biopsy can be used for detection of residual disease and cancer recurrence monitoring in dogs

Angela L. McCleary‐Wheeler, Patrick C. Fiaux, Carlos A. Ruiz-Pérez…·Andi Flory

This study evaluates a next-generation sequencing-based liquid biopsy test for detecting residual disease and monitoring cancer recurrence in dogs, finding it can identify recurrence earlier than clinical assessment.

11 citations

experimental assay

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GenomicsThe American Journal of Human GeneticsPeer-reviewedMar 28, 2023

Deletion mapping of regulatory elements for GATA3 reveals a distal T helper 2 cell enhancer involved in allergic diseases

Hsiuyi V. Chen, Michael H. Lorenzini, Shanna N. Lavalle…·Graham McVicker

The paper identifies a distal enhancer for GATA3 involved in allergic diseases by combining GWAS signals with deletion mapping in T helper 2 cells.

18 citations

humanbulk RNA-seq

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BioinformaticsPLoS Computational BiologyPeer-reviewedSep 16, 2020

Discovering functional sequences with RELICS, an analysis method for tiling CRISPR screens

Patrick C. Fiaux, Hsiuyi V. Chen, Poshen B. Chen…·Graham McVicker

RELICS is a Bayesian method for analyzing tiling CRISPR screens to discover functional genomic sequences with higher resolution than existing approaches.

12 citations

CRISPR screenBayesian inference

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