Author

Aaron J. Ho

Salk Institute for Biological Studies

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Graham McVickeriD· 3 shared Karthyayani Sajeev· 2 shared Michael H. LorenziniiD· 2 shared Shanna N. LavalleiD· 2 shared Aaron R. CheniD· 1 shared Abraham A. PalmeriD· 1 shared Apurva S. ChitreiD· 1 shared Ariana Fonseca· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersGenomics

Graham McVickerORCID

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3 papers

Recent·Most cited

Joint single-cell capture of Cas9 edits and transcriptomes reveals on- and off-target effects on gene expression

Michael H. Lorenzini, Brad Balderson, Shanna N. Lavalle, Karthyayani Sajeev, Aaron J. Ho, Madelyn Light, Olalekan H. Usman, Gavin Kurgan, Graham McVicker

Superb-seq captures single-cell Cas9 edits and transcriptomes, revealing on- and off-target effects on gene expression in over 34,000 cells.

bioRxiv · Feb 7, 2025 · PreprintGenomics

Deletion mapping of regulatory elements for GATA3 reveals a distal T helper 2 cell enhancer involved in allergic diseases

Hsiuyi V. Chen, Michael H. Lorenzini, Shanna N. Lavalle, Karthyayani Sajeev, Ariana Fonseca, Patrick C. Fiaux, Arko Sen, Ishika Luthra, Aaron J. Ho, Aaron R. Chen, Karthik Guruvayurappan, Carolyn O’Connor, Graham McVicker

The paper identifies a distal enhancer for GATA3 involved in allergic diseases by combining GWAS signals with deletion mapping in T helper 2 cells.

The American Journal of Human Genetics · Mar 28, 2023Peer-reviewedGenomics

Cocaine addiction-like behaviors are associated with long-term changes in gene regulation, energy metabolism, and GABAergic inhibition within the amygdala

Jessica Zhou, Giordano de Guglielmo, Aaron J. Ho, Marsida Kallupi, Narayan Prasad Pokhrel, Hairi Li, Apurva S. Chitre, Daniel B. Munro, Pejman Mohammadi, Lieselot L. G. Carrette, Olivier George, Abraham A. Palmer, Graham McVicker, Francesca Telese

The paper identifies cell type-specific gene regulatory changes in the amygdala of rats with varying cocaine addiction-like behaviors, linking them to energy metabolism, GABAergic inhibition, and chromatin accessibility.

bioRxiv · Sep 8, 2022 · PreprintGenomics