Larissa G. P. Langhi Prata

This study identifies salvianolic acids as natural senolytics that enhance lifespan and healthspan in aged mice by targeting senescent cells through redox modulation and inducing apoptosis and ferroptosis.

This study shows that syndecan-1 promotes AT2 cell senescence in lung fibrosis, contributing to fibrotic remodeling and suggesting it as a therapeutic target.

This study identifies dihydromyricetin as a natural senotherapeutic agent that targets senescent cells via PRDX2, alleviating age-related diseases like cancer and Alzheimer's.

This study examines age and sex effects on MDSCs in sepsis using single-cell RNA sequencing, finding differences in expansion, transcriptome, and metabolism.