Author

Utkarsh Tripathi

Mayo ClinicORCID 0000-0002-7101-8430Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Utkarsh Tripathi1 paper

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

James L. KirklandiD· 2 shared Tamar PirtskhalavaiD· 2 shared Tamar TchkoniaiD· 2 shared Adam L Jaspersen· 1 shared Alexander S. GalkiniD· 1 shared Allyson K. PalmeriD· 1 shared Andrea StojakoviciD· 1 shared Anthony Sheu· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

James L. KirklandORCID

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2 papers

Recent·Most cited

Senolytic-Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers

Utkarsh Tripathi, Masayoshi Suda, Vagisha Kulshreshtha, Bryan Thomas Piatkowski, Allyson K. Palmer, Nino Giorgadze, Christina L. Inman, Nathan S. Gasek, Ming Xu, Kurt O. Johnson, Tamar Pirtskhalava, Selim Chaib, Larissa G. P. Langhi Prata, Yi Zhun Zhu, Renuka Kandhaya‐Pillai, , James L. Kirkland

Aging Cell · Dec 29, 2025Peer-reviewedCell Biology

Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimers mouse model

Andrea Stojakovic, Sergey Trushin, Anthony Sheu, Layla Khalili, Su-Youne Chang, Xing Li, Trace A. Christensen, Jeffrey L. Salisbury, Rachel E. Geroux, Benjamin Gateno, Padraig J. Flannery, Mrunal K. Dehankar, Cory C. Funk, Jordan Maximillian Wilkins, Анна Степанова, , Eugenia V. Trushina

The paper shows that partial inhibition of mitochondrial complex I protects against neurodegeneration in Alzheimer's mice by improving energy homeostasis, synaptic function, and reducing inflammation.

Communications Biology · Jan 8, 2021Peer-reviewedNeuroscience