Author
German Cancer Research CenterORCID 0000-0001-9619-4329Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Annabell Szymansky, Falk Hertwig, Annika Winkler…·Johannes Hubertus Schulte
This study develops a method to detect minimal residual disease in neuroblastoma using ecDNA breakpoints, achieving high sensitivity and specificity in bone marrow samples.
Loélia Babin, Elissa Andraos, Steffen Fuchs…·Fabienne Meggetto
The paper identifies circZBTB46 as a driver of crizotinib resistance in ALK-positive lymphomas and shows its targeting restores drug sensitivity.
Laura Grunewald, Lena Andersch, Konstantin Helmsauer…·Annette Künkele
This paper shows that high MYCN levels in neuroblastoma reduce L1CAM expression, limiting CAR T cell efficacy, and that inhibiting MYCN with MLN8237 restores L1CAM and enhances CAR T cell activity.