Author

James MacDonald

University of WashingtonORCID 0000-0001-9620-7353Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Theo K. BammleriD· 3 shared A. N. Meleshko· 1 shared Alison G. PaquetteiD· 1 shared Amanda J. HaackiD· 1 shared Anne H SkakkebaekiD· 1 shared Ashleigh B. ThebergeiD· 1 shared Camille Groneck· 1 shared Carmen J. MarsitiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersSystems Biology

Theo K. BammlerORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintAug 24, 2026

Placental microRNA signatures of spontaneous preterm birth

Mariana Parenti, Elizabetth M Kennedy, Evan J. Firsick…·Alison G. Paquette

This study identifies microRNA signatures associated with spontaneous preterm birth and links them to target genes involved in immune signaling and oxidative phosphorylation.

DOI 10.64898/2026.08.21.746278

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintApr 21, 2026

Cell-type specific allelic dampening of sex-linked genes in sex chromosome aneuploidy

Gala N. Filippova, Elliott Sanger, James MacDonald…·Christine M. Distèche

The paper investigates how sex chromosome aneuploidy affects gene expression and DNA methylation in different cell types, revealing cell-type specific dosage compensation mechanisms.

DOI 10.64898/2026.04.16.719032

humanbulk RNA-seq

𝕏 PostBluesky

BioengineeringAnalytical ChemistryPeer-reviewedJan 17, 2025

Your Blood is Out for Delivery: Considerations of Shipping Time and Temperature on Degradation of RNA from Stabilized Whole Blood

Filip Stefanovic, Lauren G. Brown, James MacDonald…·Ashleigh B. Theberge

This study evaluates RNA degradation in homeRNA-stabilized blood under varying shipping times and temperatures, finding that samples remain suitable for RNA sequencing under typical shipping conditions.

9 citations

humanbulk RNA-seq

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