Ashleigh B. Theberge

The paper models and validates the layer widths of co-flows in open-capillary trigger valve systems using geometric parameters and experimental validation.

homeRNAdrop simplifies remote blood collection and RNA stabilization for small samples, with successful pilot testing showing adequate RNA quality and yield.

The paper develops the STEAM platform for creating suspended 3D bladder models with tunable mechanics and spatial complexity.

The paper introduces homeRNAmax, an improved blood collection and RNA stabilization platform for remote transcriptomic studies, showing it produces high-quality RNA samples and is user-friendly.

The paper optimizes pre-analytical blood collection and stabilization parameters to maintain protein integrity for remote blood sampling, finding that Protein Plus stabilizer effectively limits hemolysis and protein degradation.

This study evaluates how print orientation affects surface texture and capillary-driven flow in laser SLA-printed microchannels, finding that surface tortuosity, not roughness, better predicts flow behavior.

This study compares the transcriptomic profiles of LPS-induced immune responses in homeRNA and venous blood samples, showing homeRNA captures comparable inflammatory responses.

The paper introduces STEAM, a microfluidic platform for creating suspended tissue constructs with spatial patterning and mechanical manipulation capabilities, demonstrating its use in engineered muscle tissue.

The paper introduces STOMP, a method to create multi-regional suspended tissues for studying complex tissue interfaces, and reports altered contractile dynamics in engineered heart tissues and bone-ligament constructs.

This study introduces a criterion to detect inertial effects in capillary flows and shows how the Bosanquet equation can account for them in open-channel configurations.

The paper presents a microfluidic platform that passively generates sub-microliter volumes of purified human sperm for vitrification, preserving sperm kinematics.

This study evaluates RNA degradation in homeRNA-stabilized blood under varying shipping times and temperatures, finding that samples remain suitable for RNA sequencing under typical shipping conditions.

The paper introduces the CandyCollect O2C microfluidic system to automate antigen elution for rapid detection of group A streptococcus, showing comparable or better results than manual methods.

This paper demonstrates the implementation of trigger valves in open-channel microfluidic systems and develops a model to describe their flow dynamics.

CandyCollect is a microfluidic device for rapid, non-invasive salivary EV collection and analysis, showing consistent EV capture and concordant protein profiles.