Author

Quan Wu

RIKEN Center for Biosystems Dynamics ResearchORCID 0000-0001-9622-5367Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Fumio MatsuzakiiD· 3 shared Hiroshi KiyonariiD· 3 shared Taeko Suetsugu· 3 shared Atsunori ShitamukaiiD· 1 shared Ayaka Omori· 1 shared Charlotte ManseriD· 1 shared Hideya SakaguchiiD· 1 shared Merve BilgiciD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersDevelopmental Biology

Fumio MatsuzakiORCID

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3 papers

Recent·Most cited

Epigenetic-metabolic axis in the temporal scaling of mammalian cortical neurogenesis across species

Quan Wu, Charlotte Manser, Taeko Suetsugu, Ryo Yoshida, Hideya Sakaguchi, Yo-ichi Nabeshima, Hiroshi Kiyonari, Rubén Perez‐Carrasco, Fumio Matsuzaki

The paper identifies H3K27me3-mediated repression and -ketoglutarate as key regulators of species-specific neurogenesis timescales across mammals.

bioRxiv · Sep 23, 2025 · PreprintDevelopmental Biology

Truncated radial glia as a common precursor in the late corticogenesis of gyrencephalic mammals

Merve Bilgic, Quan Wu, Taeko Suetsugu, Atsunori Shitamukai, Yuji Tsunekawa, Tomomi Shimogori, Mitsutaka Kadota, Osamu Nishimura, Shigehiro Kuraku, Hiroshi Kiyonari, Fumio Matsuzaki

The paper identifies truncated radial glia (tRG) as a conserved progenitor subtype in ferret and human corticogenesis, showing their role in brain expansion.

eLife · Sep 18, 2023Peer-reviewedDevelopmental Biology

Selective translation of epigenetic modifiers drives the developmental clock of neural stem cells

Quan Wu, Yuichi Shichino, Takaya Abe, Taeko Suetsugu, Ayaka Omori, Hiroshi Kiyonari, Shintaro Iwasaki, Fumio Matsuzaki

This study identifies Fbl's role in driving the developmental clock of neural stem cells through translational control of H3K27me3 modifiers.

bioRxiv · Oct 8, 2020 · PreprintDevelopmental Biology