Author

Anne Metje van Genderen

Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University. Universiteitsweg 99, 3584 CG Utrecht, The NetherlandsORCID 0000-0001-9643-7722Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:organoid / primary culture· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Elena Sendino GarvíiD· 2 shared Rosalinde MasereeuwiD· 2 shared Albertien M. van EerdeiD· 1 shared Gisela G.G. SlaatsiD· 1 shared Lisa BöhliD· 1 shared Manoe Jacoba JansseniD· 1 shared Nine V.A.M. KnoersiD· 1 shared Rolf W SparidansiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersPharmacology & Toxicology

Elena Sendino GarvíORCID

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2 papers

Recent·Most cited

Gentamicin impairs nephron development in iPSC-derived kidney organoids and disrupts proximal tubular lysosomal function

Elena Sendino Garví, Wiktoria Pioruńska, Lisa Böhl, Rolf W Sparidans, Rosalinde Masereeuw, Anne Metje van Genderen

bioRxiv · Nov 3, 2026 · PreprintPharmacology & Toxicology

Loss of nephronophthisis-associated nephrocystin-1 impairs DNA damage repair in kidney organoids

Elena Sendino Garví, S. Biermans, Nine V.A.M. Knoers, Albertien M. van Eerde, Rosalinde Masereeuw, Manoe Jacoba Janssen, Gisela G.G. Slaats, Anne Metje van Genderen

This study shows that loss of nephrocystin-1 in kidney organoids impairs DNA repair, increases senescence, and leads to fibrosis, revealing a new role for NPHP1 in DNA damage response.

bioRxiv · Jun 9, 2025 · PreprintMolecular Biology