Author

Dinesh Kankanamge

Washington University in St. LouisORCID 0000-0001-9647-0258Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2

Frequent Co-Authors

Ajith KarunarathneiD· 2 shared Sithurandi UbeysingheiD· 2 shared Waruna ThotamuneiD· 2 shared Aditya Chandu· 1 shared Bryan A. CopitsiD· 1 shared Chathuri Rajarathna· 1 shared Dhanushan WijayaratnaiD· 1 shared Koshala OlupothageiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersMolecular Biology

Ajith KarunarathneORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 4, 2024

AGS3-based optogenetic GDI induces GPCR-independent Gβγ signaling and macrophage migration

Waruna Thotamune, Sithurandi Ubeysinghe, Chathuri Rajarathna…·Ajith Karunarathne

This study introduces an optogenetic GDI tool to induce Gβγ signaling independently of GPCRs and demonstrates its ability to trigger macrophage migration.

1 citation

experimental assay

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Molecular BiologyACS Synthetic BiologyPeer-reviewedDec 13, 2023

Spatiotemporal optical control of Gαq-PLCβ interactions

Sithurandi Ubeysinghe, Dinesh Kankanamge, Waruna Thotamune…·Ajith Karunarathne

This paper introduces an optogenetic tool to control GqGTP-PLCβ interactions and shows its role in regulating cell migration through competition with RhoGEFs.

11 citations

experimental assay

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