Uma T. Shankavaram

The paper introduces CPSM, an R package that provides an automated machine learning pipeline for predicting individual cancer patient survival probabilities using multi-omics data.

The paper identifies a de novo TLK1 mutation linked to neurodevelopmental disorder and immunodeficiency, showing impaired kinase activity and altered cytokine responses.

This study identifies SIRT1's role in regulating DNA damage signaling via interaction with the PP4 phosphatase complex, showing SIRT1 inhibits PP4 to modulate key DDR markers.