Ivan L. Salazar

This study shows that loss of CLN3 disrupts lysosomal lipid metabolism, leading to nuclear envelope lipid changes, DNA damage, and YAP1-driven apoptosis in Batten disease models.

This study shows that activating the 20S proteasome core particle prevents cell death in cortical neurons under oxygen- and glucose-deprivation conditions.

This study shows that physioxia-modulated UC-MSC secretome better preserves neuronal network and translation processes in an in vitro HIE model than traditional UC-MSCs.