Author

Jyoti Rana

City Of Hope National Medical CenterORCID 0000-0001-9683-4592Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Farooq SyediD· 2 shared Abigail TwoyiD· 1 shared Alexandra Coomans de BrachèneiD· 1 shared Ângela Castela· 1 shared Anup R. SharmaiD· 1 shared Arnaud ZaldumbideiD· 1 shared Carmella Evans‐MolinaiD· 1 shared CATE SPEAKEiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Farooq SyedORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintApr 2, 2026

Soluble LAG-3 Identifies a Dynamic Early T Cell Activation Window in self-reactivity, Type 1 Diabetes, and Broader Immune Responses.

Saptarshi Roy, Megan Lynn Proffer, Farooq Syed…·Jon D. Piganelli

This study identifies soluble LAG-3 (sLAG-3) as an early biomarker of T cell activation in type 1 diabetes, detectable before islet autoantibody development and associated with beta-cell stress and high-risk HLA genotypes.

1 citation

mousehuman

PhysiologyEBioMedicinePeer-reviewedMay 6, 2025

Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice

Farooq Syed, Olivia Ballew, Chih‐Chun Lee…·Carmella Evans‐Molina

This study shows that TYK2 inhibitors reduce islet inflammation and delay type 1 diabetes onset in mice by modulating immune and endocrine responses.

24 citationstop 1%

mouseexperimental assay